Lewis J Rubin Selected Research

Connective Tissue Diseases (Connective Tissue Disease)

7/2017	Initial combination therapy with ambrisentan and tadalafil in connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH): subgroup analysis from the AMBITION trial.
1/2017	Selexipag for the treatment of connective tissue disease-associated pulmonary arterial hypertension.
3/2014	Long-term results from the EARLY study of bosentan in WHO functional class II pulmonary arterial hypertension patients.
4/2012	ARIES-3: ambrisentan therapy in a diverse population of patients with pulmonary hypertension.
1/2009	Hemodynamics and epoprostenol use are associated with thrombocytopenia in pulmonary arterial hypertension.
10/2008	Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial.
12/2007	Sildenafil for pulmonary arterial hypertension associated with connective tissue disease.
11/2005	Sildenafil citrate therapy for pulmonary arterial hypertension.
8/2005	Evaluation and management of the patient with pulmonary arterial hypertension.
8/2004	Treprostinil, a prostacyclin analogue, in pulmonary arterial hypertension associated with connective tissue disease.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Lewis J Rubin Research Topics

Disease

86	Pulmonary Arterial Hypertension 01/2022 - 01/2002
26	Pulmonary Hypertension 01/2018 - 03/2002
11	Connective Tissue Diseases (Connective Tissue Disease) 07/2017 - 03/2002
10	Dyspnea (Shortness of Breath) 07/2013 - 03/2002
9	Disease Progression 01/2022 - 07/2002
9	Pain (Aches) 07/2016 - 03/2002
9	Familial Primary Pulmonary Hypertension 02/2012 - 07/2002
8	Headache (Headaches) 12/2015 - 10/2008
6	Hypertension (High Blood Pressure) 12/2015 - 01/2002
6	Nausea 12/2015 - 10/2008
5	Diarrhea 12/2015 - 11/2005
4	Heart Failure 01/2018 - 07/2002
4	Vascular Diseases (Vascular Disease) 01/2018 - 07/2002
3	Congenital Heart Defects (Congenital Heart Defect) 01/2019 - 10/2008
3	Flushing 09/2013 - 11/2005
3	Hypoxia (Hypoxemia) 04/2012 - 06/2004
2	Left Ventricular Dysfunction 12/2019 - 01/2018
2	Heart Diseases (Heart Disease) 01/2018 - 11/2012
2	Sepsis (Septicemia) 07/2016 - 03/2002
2	Edema (Dropsy) 03/2014 - 11/2012
2	Cough 02/2013 - 12/2011
2	Lung Diseases (Lung Disease) 11/2012 - 06/2007
2	Systemic Scleroderma (Systemic Sclerosis) 02/2012 - 11/2011
2	Dyspepsia (Indigestion) 10/2008 - 11/2005
2	Clinical Deterioration 08/2002 - 07/2002
2	Syncope (Fainting) 08/2002 - 03/2002
1	Rare Diseases (Rare Disease) 01/2019
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2018
1	Pulmonary Heart Disease (Cor Pulmonale) 01/2018
1	Weight Gain 01/2018
1	Nasopharyngitis 08/2013
1	Anemia 08/2013
1	Drug-Related Side Effects and Adverse Reactions 10/2012
1	Neoplasms (Cancer) 10/2012
1	Chest Pain (Chest Pains) 12/2011
1	Vomiting 12/2011
1	Thrombocytopenia (Thrombopenia) 01/2009
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 10/2008
1	Asymptomatic Diseases 09/2006

Drug/Important Bio-Agent (IBA)

22	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2021 - 03/2002
21	Endothelin Receptor AntagonistsIBA 01/2019 - 01/2002
16	treprostinil FDA Link 01/2021 - 03/2002
14	ambrisentan FDA Link 12/2019 - 07/2005
12	Bosentan (Tracleer)FDA Link 03/2014 - 01/2002
10	selexipagIBA 01/2022 - 12/2015
10	macitentanIBA 01/2018 - 08/2013
9	ProstaglandinsIBA 07/2016 - 08/2004
7	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2019 - 05/2005
7	Pharmaceutical PreparationsIBA 02/2014 - 06/2004
7	Sildenafil Citrate (Viagra)FDA Link 01/2014 - 11/2005
6	Tadalafil (Cialis)FDA Link 12/2019 - 08/2015
6	Endothelins (Endothelin)IBA 10/2012 - 01/2002
5	Epoprostenol ReceptorsIBA 01/2022 - 12/2015
5	riociguatIBA 05/2017 - 07/2013
5	Iloprost (Ventavis)FDA Link 02/2013 - 08/2002
4	FenfluramineIBA 01/2009 - 08/2005
3	pro-brain natriuretic peptide (1-76)IBA 01/2019 - 07/2013
3	Oxygen (Dioxygen)IBA 01/2018 - 06/2004
3	DiureticsIBA 01/2018 - 06/2004
3	Phosphodiesterase 5 InhibitorsIBA 12/2015 - 09/2006
3	Endothelin Receptors (Endothelin Receptor)IBA 11/2004 - 03/2002
2	SolutionsIBA 01/2021 - 09/2005
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 09/2004
2	Soluble Guanylyl CyclaseIBA 05/2015 - 07/2013
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2009 - 10/2008
2	sitaxsentanIBA 01/2009 - 01/2002
2	Cocaine (Cocaine HCl)IBA 12/2006 - 08/2005
2	CollagenIBA 08/2005 - 07/2002
1	Complement System Proteins (Complement)IBA 01/2019
1	Adrenergic Agents (Adrenergic Drugs)IBA 01/2016
1	beta Adrenergic ReceptorsIBA 02/2015
1	Hormones (Hormone)IBA 03/2014
1	Hemoglobins (Hemoglobin)IBA 03/2014
1	Excipients (Suspending Agents)IBA 02/2014
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 02/2014
1	Arginine (L-Arginine)FDA Link 02/2014
1	Mannitol (Osmitrol)FDA LinkGeneric 02/2014
1	7-(N-(3-aminopropyl)amino)heptan-2-oneIBA 02/2012
1	ametantrone (HAQ)IBA 11/2011
1	Phosphodiesterase InhibitorsIBA 02/2010
1	TRPC6 Cation ChannelIBA 05/2009
1	Transaminases (Aminotransferases)IBA 01/2009
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 10/2008
1	PropionatesIBA 06/2008
1	Radioisotopes (Radionuclides)IBA 06/2007
1	Methamphetamine (Desoxyn)FDA LinkGeneric 12/2006
1	Amphetamine (Amfetamine)FDA LinkGeneric 12/2006
1	Dexfenfluramine (Redux)IBA 09/2006

Therapy/Procedure

50	Therapeutics 01/2022 - 03/2002
4	Endarterectomy (Thromboendarterectomy) 12/2008 - 02/2003
3	Subcutaneous Infusions 07/2016 - 03/2002
3	Cardiac Catheters 02/2009 - 12/2006
2	Denervation 01/2020 - 12/2015
2	Lung Transplantation 08/2013 - 09/2006
1	Inhalation Administration 01/2021
1	Catheters 07/2016
1	Operative Surgical Procedures 06/2010
1	Metered Dose Inhalers (Metered Dose Inhaler) 02/2009
1	Drug Tapering 01/2009
1	Activities of Daily Living (ADL) 06/2008